Harrison replaces Santos.
John Ward has made one change to the side that beat York City last weekend.
Ellis Harrison comes in to replace Alefe Santos in the starting line up.
Matt Harrold and Eliot Richards are both on the bench for today's game after recovering from injuries.
Bristol Rovers: Steve Mildenhall, Michael Smith, Tom Parkes, Mark McChrystal, Lee Brown, Ellis Harrison, Tom Lockyer, Ollie Norburn, John-Joe O’Toole, David Clarkson, Ryan Brunt
Substitutes: Garry Kenneth, Matt Gill, Conor Gough, Alefe Santos, Eliot Richards, Matt Harrold, Mitch Harding
Northampton Town: Matt Duke, Kevin Amankwaah, Matt Heath, Lee Colins, Ben Tozer, Darren Carter, Ishmel Demontagnac, Gary Deegan, Chris Hackett, Roy O'Donovan, Clive Platt.
Substitutes: Dean Snedker, Jonathan Hooper, Ivan Toney, Jacob Blyth, Matt Harriott, Connor Roberts.